Abstract
A mutation in the CYCLTR2 G-protein-coupled receptor promotes tumorigenesis in uveal melanomas.
©2016 American Association for Cancer Research.
MeSH terms
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Cell Transformation, Neoplastic / genetics
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Gene Expression Regulation, Neoplastic
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Humans
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Melanoma / genetics*
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Melanoma / metabolism
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Mutation*
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Oncogene Proteins / genetics
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Oncogene Proteins / metabolism
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Receptors, Leukotriene / genetics*
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Receptors, Leukotriene / metabolism
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Uveal Neoplasms / genetics*
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Uveal Neoplasms / metabolism
Substances
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Oncogene Proteins
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Receptors, Leukotriene
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cysteinyl leukotriene receptor 2