FRED 2: an immunoinformatics framework for Python

Bioinformatics. 2016 Jul 1;32(13):2044-6. doi: 10.1093/bioinformatics/btw113. Epub 2016 Feb 26.

Abstract

Immunoinformatics approaches are widely used in a variety of applications from basic immunological to applied biomedical research. Complex data integration is inevitable in immunological research and usually requires comprehensive pipelines including multiple tools and data sources. Non-standard input and output formats of immunoinformatics tools make the development of such applications difficult. Here we present FRED 2, an open-source immunoinformatics framework offering easy and unified access to methods for epitope prediction and other immunoinformatics applications. FRED 2 is implemented in Python and designed to be extendable and flexible to allow rapid prototyping of complex applications.

Availability and implementation: FRED 2 is available at http://fred-2.github.io

Contact: schubert@informatik.uni-tuebingen.de

Supplementary information: Supplementary data are available at Bioinformatics online.

MeSH terms

  • Computational Biology / methods*
  • Epitopes, T-Lymphocyte / chemistry*
  • Humans
  • Information Storage and Retrieval
  • Software*
  • Vaccines / chemistry
  • Vaccines / immunology

Substances

  • Epitopes, T-Lymphocyte
  • Vaccines