How will the MMR universal mass vaccination change the epidemiologic pattern of mumps? A 2012 Italian serosurvey

Am J Infect Control. 2016 Nov 1;44(11):1420-1421. doi: 10.1016/j.ajic.2016.03.012. Epub 2016 May 2.

Abstract

To investigate the changes in the epidemiologic pattern of mumps, we carried out a serosurvey among young adults from Apulia, Italy. A convenience sample of 1,764 blood donors were enrolled in 2012: 93.4% (95% confidence interval, 92.1-94.5) showed a positive antimumps immunoglobulin G titre, geometric mean titer was 2.05. Results were consistent with previously published data on the immunogenicity of mumps vaccine but showed a lack of immunity (10% of people aged 18-26 years susceptible for mumps). Future research must be focused on the long-time immunogenicity of the mumps vaccine.

Keywords: Immunogenicity; Young adults susceptibility.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Antibodies, Viral / blood
  • Disease Susceptibility
  • Female
  • Humans
  • Immunoglobulin G / blood
  • Italy / epidemiology
  • Male
  • Mass Vaccination / statistics & numerical data*
  • Measles-Mumps-Rubella Vaccine / administration & dosage*
  • Middle Aged
  • Mumps / epidemiology*
  • Mumps / prevention & control*
  • Seroepidemiologic Studies
  • Surveys and Questionnaires
  • Young Adult

Substances

  • Antibodies, Viral
  • Immunoglobulin G
  • Measles-Mumps-Rubella Vaccine