Killing me softly: microparticles target deformable cells

Jens Hamann; Michael Overholtzer

doi:10.1038/cr.2016.54

Killing me softly: microparticles target deformable cells

Cell Res. 2016 Jun;26(6):637-8. doi: 10.1038/cr.2016.54. Epub 2016 May 10.

Authors

Jens Hamann¹, Michael Overholtzer¹

Affiliation

¹ Cell Biology Program and Louis V Gerstner Jr Graduate School of Biomedical Sciences, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA.

Abstract

Mechanical deformability is known to increase during cancer progression. Now Ma et al. identify a therapeutic strategy that targets deformable cells by microparticle-based drug delivery.

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MeSH terms

Cell-Derived Microparticles*
Drug Delivery Systems
Drug Resistance
Humans
Neoplasms*