The Canadian Agency for Drugs and Technologies in Health (CADTH) will undertake a systematic review to compare the efficacy and safety of disease-modifying agents for patients with relapsing-remitting multiple sclerosis (RRMS), and will examine their cost-effectiveness. The review will include disease-modifying agents that are currently available in Canada (interferon beta-1a and -1b, natalizumab, glatiramer acetate, fingolimod), and a number of agents that are newly emerging and not yet approved in Canada (teriflunomide, dimethyl fumarate, and alemtuzumab).
The systematic review and cost-effectiveness evidence will be reviewed by the Canadian Drug Expert Committee (CDEC) for the purpose of making recommendations. Recommendations and advice provided by CDEC are provided to CADTH to inform participating jurisdictions.
Copyright © 2012 CADTH.