Age-related changes in precorneal tear film stability

Optom Vis Sci. 1989 Mar;66(3):175-8. doi: 10.1097/00006324-198903000-00008.


For several years it has been known that the production rate of tears declines as age increases. Reports suggest that this reduction is more apparent in females than in males. Using a noninvasive method we report that a significant linear reduction in precorneal tear film stability occurs between the ages of 8 and 80 years. However, we found no significant differences in tear film stability between males and females.

Publication types

  • Comparative Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aging*
  • Child
  • Child, Preschool
  • Female
  • Fluoresceins
  • Humans
  • Male
  • Middle Aged
  • Sex Factors
  • Tears / analysis
  • Tears / metabolism*
  • Time Factors


  • Fluoresceins