Combination chemotherapy with 5-fluorouracil and dacarbazine in advanced medullary thyroid cancer, a possible alternative?

Acta Oncol. 2016 Aug;55(8):1064-6. doi: 10.3109/0284186X.2016.1157264. Epub 2016 May 13.
No abstract available

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Carcinoma, Neuroendocrine / drug therapy*
  • Carcinoma, Neuroendocrine / genetics*
  • Carcinoma, Neuroendocrine / mortality
  • DNA Methylation
  • DNA Modification Methylases / genetics
  • DNA Repair Enzymes / genetics
  • Dacarbazine / administration & dosage
  • Fluorouracil / administration & dosage
  • Humans
  • Mutation
  • Promoter Regions, Genetic
  • Proto-Oncogene Proteins c-ret / genetics
  • Thyroid Neoplasms / drug therapy*
  • Thyroid Neoplasms / genetics*
  • Thyroid Neoplasms / mortality
  • Treatment Outcome
  • Tumor Suppressor Proteins / genetics

Substances

  • Tumor Suppressor Proteins
  • Dacarbazine
  • DNA Modification Methylases
  • MGMT protein, human
  • Proto-Oncogene Proteins c-ret
  • RET protein, human
  • DNA Repair Enzymes
  • Fluorouracil

Supplementary concepts

  • Thyroid cancer, medullary