Sleepless in CKD: a novel risk factor for CKD progression?

Mark J Sarnak; Mark Unruh

doi:10.1016/j.kint.2016.02.028

Sleepless in CKD: a novel risk factor for CKD progression?

Kidney Int. 2016 Jun;89(6):1187-8. doi: 10.1016/j.kint.2016.02.028.

Authors

Mark J Sarnak¹, Mark Unruh²

Affiliations

¹ Division of Nephrology, Tufts University School of Medicine, Boston, Massachusetts, USA. Electronic address: msarnak@tuftsmedicalcenter.org.
² Renal Division, Department of Internal Medicine, University of New Mexico, Albuquerque, New Mexico, USA; Renal Section, Medicine Service, Department of Medicine, Raymond G. Murphy VA Medical Center, School of Medicine, University of New Mexico, Albuquerque, New Mexico, USA.

PMID: 27181774
DOI: 10.1016/j.kint.2016.02.028

Abstract

Disorders of sleep have been associated with adverse outcomes in both the general population and in patients with chronic kidney disease. McMullan et al. add to this literature by demonstrating an association between short sleep duration and more rapid decline in glomerular filtration rate. We discuss the potential implications of these results but also offer some caution in over-interpretation of the data, given limitations in both the assessment of sleep as well as the kidney outcomes.

Keywords: cardiovascular disease; chronic kidney disease.

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MeSH terms

Disease Progression*
Glomerular Filtration Rate
Humans
Kidney
Renal Insufficiency, Chronic*
Risk Factors