Guidewire and microcatheter utilization patterns during antegrade wire escalation in chronic total occlusion percutaneous coronary intervention: Insights from a contemporary multicenter registry

Catheter Cardiovasc Interv. 2017 Mar 1;89(4):E90-E98. doi: 10.1002/ccd.26568. Epub 2016 May 17.


Objectives: We sought to describe contemporary guidewire and microcatheter utilization for antegrade wire escalation (AWE) during chronic total occlusion (CTO) percutaneous coronary intervention (PCI).

Background: Equipment utilization for AWE has been variable and evolving over time.

Methods: We examined device utilization during 694 AWE attempts in 679 patients performed at 15 experienced US centers between May 2012 and April 2015.

Results: Mean age was 65.6 ± 9.7 years, and 85% of the patients were men. Successful wiring occurred in 436 AWE attempts (63%). Final technical and procedural success was 91% and 89%, respectively. The mean number of guidewire types used for AWE was 2.2 ± 1.4. The most frequently used guidewire types were the Pilot 200 (Abbott Vascular, 56% of AWE procedures), Fielder XT (Asahi Intecc, 45%), and the Confianza Pro 12 (Asahi Intecc, 28%). The same guidewires were the ones that most commonly crossed the occlusion: Pilot 200 (36% of successful AWE crossings), Fielder XT (20%), and Confianza Pro 12 (11%). A microcatheter or over-the-wire balloon was used for 81% of AWE attempts; the Corsair microcatheter (Asahi Intecc) was the most commonly used (44%). No significant association was found between guidewire type and incidence of major adverse cardiac events (MACE).

Conclusions: Our contemporary, multicenter CTO PCI registry demonstrates that the most commonly used wires for AWE are polymer-jacketed guidewires. "Stiff" and polymer-jacketed guidewires appear to provide high crossing rates without an increase in MACE or perforation, and may thus be considered for upfront use. © 2016 Wiley Periodicals, Inc.

Keywords: antegrade approach; chronic total occlusion; guidewires; percutaneous coronary intervention; technical success; technique.

Publication types

  • Clinical Trial
  • Multicenter Study

MeSH terms

  • Aged
  • Cardiac Catheters / statistics & numerical data*
  • Chronic Disease
  • Coronary Angiography
  • Coronary Occlusion / diagnosis
  • Coronary Occlusion / surgery*
  • Equipment Design
  • Female
  • Follow-Up Studies
  • Humans
  • Male
  • Miniaturization
  • Percutaneous Coronary Intervention / instrumentation*
  • Registries*
  • Retrospective Studies
  • Stents
  • Treatment Outcome