Incidence and risk factors for early postoperative reintubations

J Clin Anesth. 2016 Jun;31:80-9. doi: 10.1016/j.jclinane.2015.12.038. Epub 2016 Apr 12.

Abstract

Study objective: Reintubations are associated with significantly increased morbidity and mortality, increased hospital length of stay, and increased cost. Our aim was to assess the national incidence and associated risk factors for unanticipated early postoperative reintubations.

Design: Using the National Anesthesia Clinical Outcomes Registry (NACOR) from 2010 to 2014, multivariate logistic regression was fitted to determine if various patient, surgical, intraoperative, or provider data were associated with unanticipated early postoperative reintubations.

Setting: NACOR from 2010 to 2014.

Patients: A total of 2,970,904 cases were included. Multivariate analysis controlled for patient age, sex, and American Society of Anesthesiologists (ASA) Physical Status.

Interventions: None.

Measurements: We report odds ratios (ORs) and 95% confidence intervals (CIs) for the relative odds of an association of predictor variable with reintubations.

Main results: The incidence of unanticipated early postoperative reintubations from the NACOR database was 0.061%. Overall, reintubations were more likely in the extremes of age (age under 1 year had OR = 3.46, 95% confidence interval [CI] = 2.64-4.52 and age 80+ has OR = 1.80, 95% CI = 1.50-2.15 when compared with age 19-49 years), patients with ASA Physical Status 3 and 4 (OR = 4.06, 95% CI = 3.38-4.86 and OR = 8.65, 95% CI = 7.11-10.52, respectively, when compared with ASA 1), longer case duration (180-360 minutes OR = 13.87, 95% CI = 10.7-17.98 when compared with cases less than 60 minute duration), and cases that had a resident trainee present (OR = 1.22, 95% CI = 1.03-1.44 when compared with no resident present). Thoracic and vascular surgical procedures had the highest rates of reintubation when compared with general surgery (OR = 3.47, 95% CI = 2.81-4.28 and OR = 1.51, 95% CI = 1.24-1.82, respectively).

Conclusions: A number of risk factors correlate with an increased risk of unanticipated early postoperative reintubations, including extremes of age, patients with greater medical comorbidities, longer operations, and patients undergoing thoracic procedures.

Keywords: Airway management; Outcomes; PACU; Quality improvement; Reintubation; Respiratory failure.

MeSH terms

  • Adolescent
  • Adult
  • Age Factors
  • Aged
  • Aged, 80 and over
  • Airway Extubation
  • Airway Management / statistics & numerical data
  • Child
  • Child, Preschool
  • Female
  • Humans
  • Incidence
  • Infant
  • Infant, Newborn
  • Intubation, Intratracheal / statistics & numerical data*
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology*
  • Postoperative Complications / therapy
  • Registries
  • Respiratory Insufficiency / epidemiology
  • Respiratory Insufficiency / therapy
  • Retreatment / statistics & numerical data
  • Retrospective Studies
  • Risk Factors
  • United States / epidemiology
  • Young Adult