Whole exome sequencing reveals activating JAK1 and STAT3 mutations in breast implant-associated anaplastic large cell lymphoma anaplastic large cell lymphoma

Haematologica. 2016 Sep;101(9):e387-90. doi: 10.3324/haematol.2016.146118. Epub 2016 May 19.
No abstract available

Publication types

  • Case Reports
  • Letter

MeSH terms

  • Adult
  • Ascitic Fluid / immunology
  • Breast Implants / adverse effects*
  • Breast Neoplasms / diagnostic imaging
  • Breast Neoplasms / etiology
  • Breast Neoplasms / genetics*
  • Breast Neoplasms / radiotherapy
  • Female
  • Humans
  • Immunophenotyping
  • Janus Kinase 1 / genetics*
  • Janus Kinase 1 / metabolism
  • Lymphoma, Large-Cell, Anaplastic / diagnostic imaging
  • Lymphoma, Large-Cell, Anaplastic / etiology
  • Lymphoma, Large-Cell, Anaplastic / genetics*
  • Lymphoma, Large-Cell, Anaplastic / radiotherapy
  • Middle Aged
  • Mutation*
  • STAT3 Transcription Factor / genetics*
  • STAT3 Transcription Factor / metabolism
  • Whole Exome Sequencing*

Substances

  • STAT3 Transcription Factor
  • JAK1 protein, human
  • Janus Kinase 1