Residential cognitive-behavioral weight-loss intervention for obesity with and without binge-eating disorder: A prospective case-control study with five-year follow-up

Int J Eat Disord. 2016 Jul;49(7):723-30. doi: 10.1002/eat.22549. Epub 2016 May 20.


Objective: The aim of this prospective case-control study was to compare the long-term effects of a residential cognitive-behavioral treatment (CBT) for weight loss in severely obese patients with and without binge-eating disorder (BED).

Methods: We assessed weight-loss outcomes and psychological impairment in 54 severely obese female patients with BED and 54 patients matched by age, gender, and body mass index (BMI) without BED admitted to a residential CBT program. Body weight was measured at baseline and at 6-month follow-up and was reported by patients in a telephone interview at 5-year follow-up. Depression, eating disorder psychopathology, general psychopathology, and quality of life were assessed using validated instruments at baseline and at 6-month follow-up.

Results: Obese patients with and without BED had similar weight loss at 6-month and 5-year follow-ups. Although both groups showed improved psychosocial variables, at 6 months the BED group maintained higher psychological impairment. Nevertheless, at 5-year follow-up more than half of the BED participants were no longer classifiable as having BED.

Discussion: The presence of BED does not affect weight-loss outcome in obese patients treated with the residential CBT for weight loss program considered. © 2016 Wiley Periodicals, Inc.(Int J Eat Disord 2016; 49:723-730).

Keywords: binge-eating disorder; cognitive-behavioral treatment; obesity; residential treatment; weight loss.

MeSH terms

  • Adult
  • Binge-Eating Disorder / complications*
  • Case-Control Studies
  • Cognitive Behavioral Therapy*
  • Female
  • Humans
  • Middle Aged
  • Obesity / complications
  • Obesity / psychology
  • Obesity / therapy*
  • Prospective Studies
  • Quality of Life
  • Treatment Outcome
  • Weight Loss