Is Chronic Obstructive Pulmonary Disease Caused by Wood Smoke a Different Phenotype or a Different Entity?

Arch Bronconeumol. 2016 Aug;52(8):425-31. doi: 10.1016/j.arbres.2016.04.004. Epub 2016 May 17.
[Article in English, Spanish]


Around 40% of the world's population continue using solid fuel, including wood, for cooking or heating their homes. Chronic exposure to wood smoke is a risk factor for developing chronic obstructive pulmonary disease (COPD). In some regions of the world, this can be a more important cause of COPD than exposure to tobacco smoke from cigarettes. Significant differences between COPD associated with wood smoke (W-COPD) and that caused by smoking (S-COPD) have led some authors to suggest that W-COPD should be considered a new COPD phenotype. We present a review of the differences between W-COPD and S-COPD. On the premise that wood smoke and tobacco smoke are not the same and the physiopathological mechanisms they induce may differ, we have analyzed whether W-COPD can be considered as another COPD phenotype or a distinct nosological entity.

Keywords: Biomasa; Biomass; Chronic obstructive pulmonary disease; Enfermedad pulmonar obstructiva crónica; Fenotipo; Humo de leña; Phenotype; Wood smoke.

Publication types

  • Comparative Study

MeSH terms

  • Age Factors
  • Biomass
  • Developing Countries
  • Diagnostic Techniques, Respiratory System
  • Female
  • Fossil Fuels / adverse effects
  • Humans
  • Hypertension, Pulmonary / etiology
  • Inhalation Exposure
  • Male
  • Meta-Analysis as Topic
  • Phenotype
  • Pulmonary Disease, Chronic Obstructive / classification*
  • Pulmonary Disease, Chronic Obstructive / diagnosis
  • Pulmonary Disease, Chronic Obstructive / etiology
  • Pulmonary Disease, Chronic Obstructive / physiopathology
  • Pulmonary Emphysema / etiology
  • Quality of Life
  • Sex Factors
  • Smoke / adverse effects*
  • Symptom Assessment
  • Tobacco / adverse effects*
  • Tobacco Smoke Pollution / adverse effects
  • Treatment Outcome
  • Wood*


  • Fossil Fuels
  • Smoke
  • Tobacco Smoke Pollution