From regions to connections and networks: new bridges between brain and behavior

Curr Opin Neurobiol. 2016 Oct;40:1-7. doi: 10.1016/j.conb.2016.05.003. Epub 2016 May 19.


Connections and interactions among distributed brain areas are increasingly recognized as the basis for cognitive operations and a diverse repertoire of behaviors. Analytic advances have allowed for brain connectivity to be represented and quantified at multiple levels: from single connections to communities and networks. This review traces the trajectory of network neuroscience, focusing on how connectivity patterns can be related to cognition and behavior. As recent initiatives for open science provide access to imaging and phenotypic data with great detail and depth, we argue that approaches capable of directly modeling multivariate relationships between brain and behavior will become increasingly important in the field.

Publication types

  • Review

MeSH terms

  • Behavior / physiology*
  • Brain / physiology*
  • Cognition / physiology
  • Humans
  • Nerve Net / physiology*
  • Neurosciences / trends