Elastase 1 and chymotrypsin B in pancreatic juice and feces

Clin Biochem. 1989 Apr;22(2):85-9. doi: 10.1016/s0009-9120(89)80003-7.


A chymotrypsin-like protease was detected along with elastase 1 in pancreatic secretion and stool. This enzyme was isolated from necrobiotic human pancreas, purified, partially characterized and designated as chymotrypsin B. Quantitative studies by rocket immunoelectrophoresis indicated that neither elastase 1 nor chymotrypsin B was degraded during intestinal passage. On the basis of a clinical study, both enzymes were found to reflect pancreatic function.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Chymotrypsin / metabolism*
  • Electrophoresis, Polyacrylamide Gel
  • Feces / enzymology*
  • Humans
  • Immunoelectrophoresis
  • Kinetics
  • Pancreatic Elastase / metabolism*
  • Pancreatic Juice / enzymology*


  • Chymotrypsin
  • Pancreatic Elastase