Hutchinson-Gilford progeria syndrome: report of a Libyan family and evidence of autosomal recessive inheritance

Clin Genet. 1989 Feb;35(2):125-32. doi: 10.1111/j.1399-0004.1989.tb02917.x.


A Libyan family with the Hutchinson-Gilford progeria syndrome affecting three children of two sisters is described. The proband was ascertained because of repeated unhealing fractures. The pattern of inheritance appeared autosomal recessive.

Publication types

  • Case Reports

MeSH terms

  • Child, Preschool
  • Consanguinity
  • Female
  • Genes, Recessive*
  • Humans
  • Libya
  • Male
  • Osteolysis / diagnostic imaging
  • Osteolysis / genetics
  • Pedigree
  • Progeria / diagnostic imaging
  • Progeria / genetics*
  • Radiography