Hutchinson-Gilford progeria syndrome: report of a Libyan family and evidence of autosomal recessive inheritance

M M Khalifa

doi:10.1111/j.1399-0004.1989.tb02917.x

Hutchinson-Gilford progeria syndrome: report of a Libyan family and evidence of autosomal recessive inheritance

Clin Genet. 1989 Feb;35(2):125-32. doi: 10.1111/j.1399-0004.1989.tb02917.x.

Author

M M Khalifa¹

Affiliation

¹ Department of Pediatrics, Queen's University, Kingston, Ontario, Canada.

PMID: 2721021
DOI: 10.1111/j.1399-0004.1989.tb02917.x

Abstract

A Libyan family with the Hutchinson-Gilford progeria syndrome affecting three children of two sisters is described. The proband was ascertained because of repeated unhealing fractures. The pattern of inheritance appeared autosomal recessive.

Publication types

Case Reports

MeSH terms

Child, Preschool
Consanguinity
Female
Genes, Recessive*
Humans
Libya
Male
Osteolysis / diagnostic imaging
Osteolysis / genetics
Pedigree
Progeria / diagnostic imaging
Progeria / genetics*
Radiography