Depression and magnesium deficiency

Int J Psychiatry Med. 1989;19(1):57-63. doi: 10.2190/nkcd-1rb1-qma9-g1vn.


The psychiatric symptoms of magnesium deficiency are unspecific, ranging from apathy to psychosis, and may be attributed to other disease processes associated with poor intake, defect absorption, or excretion of magnesium. Serum magnesium should be determined when there are symptoms consistent with magnesium deficiency and/or in conditions which can lead to a deficiency, e.g., malabsorption, malnutrition, alcoholism and diuretic treatment. A low serum value suggests magnesium deficiency, but the diagnosis is reinforced with analyses of magnesium in the urine and a loading test with magnesium. Magnesium can be given orally or intramuscular/intravenously.

Publication types

  • Case Reports

MeSH terms

  • Aged
  • Depressive Disorder / etiology*
  • Female
  • Humans
  • Ileal Diseases / surgery
  • Intestinal Obstruction / surgery
  • Magnesium Deficiency / complications*
  • Neurocognitive Disorders / etiology*
  • Postoperative Complications / etiology