Endogenous attention modulates early selective attention in psychopathy: An ERP investigation

Cogn Affect Behav Neurosci. 2016 Oct;16(5):779-88. doi: 10.3758/s13415-016-0430-7.


Psychopathic individuals are prone to act on urges without adequate consideration of future consequences or the rights of other individuals. One interpretation of this behavior is that it reflects abnormal selective attention (i.e., a failure to process information that is incongruent with their primary focus of attention; Hiatt, Schmitt, & Newman, Neuropsychology, 18, 50-59, 2004). Unfortunately, it is unclear whether this selective attention abnormality reflects top-down endogenous influences, such as the strength or specificity of attention focus (i.e., top-down set) apart from other, more exogenous (bottom-up), effects on attention. To explore this question, we used an early visual event-related potential (N2pc) in combination with a modified visual search task designed to assess the effect of early endogenous (i.e., top-down) attention on the processing of set-congruent information. The task was administered to a sample of 70 incarcerated adult males, who were assigned to high, intermediate, and low psychopathy groups using Hare's Psychopathy Checklist-Revised (Hare, 2003). Based on the assumption that their failure to process set-incongruent information reflects the exaggerated effects of endogenous attention, we predicted that participants with high psychopathy scores would show an exaggerated N2pc response to set-congruent information. The results supported the hypothesis and provide novel electrophysiological evidence that psychopathy is associated with exaggerated endogenous attention effects during early stages of processing. Further research is needed to examine the implications of this finding for the well-established failure of psychopathic individuals to process set-incongruent information and inhibit inappropriate responses.

Keywords: ERP; N2pc; Psychopathy; Selective attention.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Adult
  • Antisocial Personality Disorder / physiopathology*
  • Antisocial Personality Disorder / psychology*
  • Attention / physiology*
  • Brain / physiopathology*
  • Criminals
  • Electroencephalography
  • Evoked Potentials, Visual*
  • Humans
  • Interview, Psychological
  • Male
  • Middle Aged
  • Neuropsychological Tests
  • Photic Stimulation
  • Psychiatric Status Rating Scales
  • Reaction Time
  • Time Factors
  • Young Adult