Investigating Salmonella Eko From Various Sources in Nigeria by Whole Genome Sequencing to Identify the Source of Human Infections

PLoS One. 2016 May 26;11(5):e0156212. doi: 10.1371/journal.pone.0156212. eCollection 2016.

Abstract

Twenty-six Salmonella enterica serovar Eko isolated from various sources in Nigeria were investigated by whole genome sequencing to identify the source of human infections. Diversity among the isolates was observed and camel and cattle were identified as the primary reservoirs and the most likely source of the human infections.

MeSH terms

  • Animals
  • Camelus
  • Cattle
  • DNA, Bacterial / genetics*
  • Fishes
  • Food Microbiology*
  • Genetic Variation / genetics
  • Genome, Bacterial*
  • High-Throughput Nucleotide Sequencing / methods*
  • Humans
  • Phylogeny
  • Salmonella Infections / microbiology*
  • Salmonella enterica / classification
  • Salmonella enterica / genetics*
  • Salmonella enterica / isolation & purification*
  • Salmonella enterica / pathogenicity
  • Virulence / genetics

Substances

  • DNA, Bacterial

Grant support

This work was supported by the Danish Council for Strategic Research (grant number: 09-067103), Center for Genomic Epidemiology (www.genomicepidemiology.org), and by the World Health Organization Global Foodborne Infections Network (www.who.int/gfn).