Successful treatment continuation with a single mild partial splenic embolization for thrombocytopenia caused by oxaliplatin-based chemotherapy for advanced colon cancer

Indian J Gastroenterol. 2016 May;35(3):245-7. doi: 10.1007/s12664-016-0665-9. Epub 2016 May 27.


We report the case of a patient with advanced colon cancer receiving oxaliplatin-based chemotherapy that was able to continue systemic chemotherapy by performing mild partial splenic embolization (PSE) for thrombocytopenia caused by splenomegaly due to oxaliplatin. Mild PSE may be useful for thrombocytopenia due to splenomegaly in cancer patients because it provides more treatment opportunities.

Keywords: Colon cancer; Oxaliplatin; Partial splenic embolization; Splenomegaly; Thrombocytopenia.

Publication types

  • Case Reports

MeSH terms

  • Adult
  • Antineoplastic Combined Chemotherapy Protocols / adverse effects*
  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use*
  • Colonic Neoplasms / drug therapy*
  • Embolization, Therapeutic / methods*
  • Female
  • Humans
  • Organoplatinum Compounds / administration & dosage
  • Organoplatinum Compounds / adverse effects*
  • Oxaliplatin
  • Spleen*
  • Splenomegaly / chemically induced
  • Thrombocytopenia / chemically induced*
  • Thrombocytopenia / therapy*
  • Treatment Outcome


  • Organoplatinum Compounds
  • Oxaliplatin