Fabrication of 3D Biomimetic Microfluidic Networks in Hydrogels

Adv Healthc Mater. 2016 Sep;5(17):2153-60. doi: 10.1002/adhm.201600351. Epub 2016 May 30.

Abstract

A laser-based hydrogel degradation technique is developed that allows for local control over hydrogel porosity, fabrication of 3D vascular-derived, biomimetic, hydrogel-embedded microfluidic networks, and generation of two intertwining, yet independent, microfluidic networks in a single construct.

Keywords: biomimetic; laser-based degradation; microfluidic; tissue engineering; vascularized constructs.

Publication types

  • Research Support, Non-U.S. Gov't
  • Research Support, N.I.H., Extramural
  • Research Support, U.S. Gov't, Non-P.H.S.

MeSH terms

  • Biomimetic Materials / chemistry*
  • Hydrogels / chemistry*
  • Lab-On-A-Chip Devices*

Substances

  • Hydrogels