Single anterior approach for cervical spine fractures at C5-T1 complicating ankylosing spondylitis

Clin Neurol Neurosurg. 2016 Aug:147:1-5. doi: 10.1016/j.clineuro.2016.05.015. Epub 2016 May 17.

Abstract

Objectives: To evaluate the outcomes of anterior approach for cervical spine fractures at C5-T1 in patients with ankylosing spondylitis (AS) and study the problems encountered in diagnosis and treatment.

Patients and methods: Ten patients with AS (all males; mean age 43.7±9.4 years) underwent anterior surgeries to treat fractures at C5-T1. Skull tractions were performed on patients with fracture dislocation preoperatively. After operation, all the patients wore a cervical collar for 3 months. Plain radiographs at follow-up were reviewed. If bone fusion could not be confirmed on plain radiograph, CT scan was employed. The pre- and postoperative neurological statuses were evaluated according to the Frankel grading system. Problems encountered in diagnosis and treatments were analyzed.

Results: The mean follow-up was 41.2±22.7months. After operation, the displacements of fractures were significantly reduced(P<0.05). Bone fusions were observed in 9 patients at final follow-up. Frankel grades improved by 1.0±0.7 grade (P>0.05). Posterior complications occurred in four patients, including implants failure (n=1), subsidence of cage (n=1), hoarse voice (n=1) and pneumonias (n=2). The patient with implants failure required revision surgery and anterior-posterior fixation. Patient with subsidence of the titanium cage achieved bone fusion with prolonged cervical collar immobilization.

Conclusion: The diagnosis and treatment of cervical spine fractures at C5-T1 in AS patients are challenging, with high risk of neurological compromise and postoperative complications. The single anterior approach followed by postoperative immobilization with a cervical collar can yield acceptable results if the cases are properly selected.

Keywords: Ankylosing spondylitis; Anterior approach; Cervical spine; Fracture; Surgery; Treatment.

MeSH terms

  • Adult
  • Cervical Vertebrae / injuries
  • Cervical Vertebrae / surgery*
  • Humans
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Spinal Fractures / surgery*
  • Spondylitis, Ankylosing*
  • Thoracic Vertebrae / injuries