26S Proteasome: Hunter and Prey in Auxin Signaling

Trends Plant Sci. 2016 Jul;21(7):546-548. doi: 10.1016/j.tplants.2016.05.007. Epub 2016 May 27.

Abstract

Auxin binds to TRANSPORT INHIBITOR RESPONSE 1 and AUXIN SIGNALLING F-BOX proteins (TIR1/AFBs) and promotes the degradation of Aux/IAA transcriptional repressors. The proteasome regulator PROTEASOME REGULATOR1 (PTRE1) has now been shown to be required for auxin-mediated repression of 26S proteasome activity, thus providing new insights into the fine-tuning of the homoeostasis of Aux/IAA proteins and auxin signaling.

Keywords: auxin; proteasome activity; proteasome inhibitor.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Arabidopsis Proteins / genetics
  • Arabidopsis Proteins / metabolism
  • F-Box Proteins / genetics
  • F-Box Proteins / metabolism
  • Gene Expression Regulation, Plant / genetics
  • Gene Expression Regulation, Plant / physiology
  • Indoleacetic Acids / metabolism*
  • Proteasome Endopeptidase Complex / genetics
  • Proteasome Endopeptidase Complex / metabolism*
  • Receptors, Cell Surface / genetics
  • Receptors, Cell Surface / metabolism
  • Signal Transduction / genetics
  • Signal Transduction / physiology

Substances

  • Arabidopsis Proteins
  • F-Box Proteins
  • Indoleacetic Acids
  • Receptors, Cell Surface
  • TIR1 protein, Arabidopsis
  • Proteasome Endopeptidase Complex
  • ATP dependent 26S protease