A model for biocompatibility and its evaluation

J Biomed Eng. 1989 May;11(3):185-91. doi: 10.1016/0141-5425(89)90138-6.


Concepts of biocompatibility have changed radically in recent years. This paper describes these new concepts and the present knowledge of the components and mediators of biocompatibility and leads to the development of a model for the explanation and rationalization of these phenomena. Of particular importance is the question of the assessment or evaluation of biocompatibility. The paper concludes with comments on the need for a schedule of biocompatibility assessment procedures to take into account this new thinking.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Biocompatible Materials*
  • Connective Tissue / physiology
  • Models, Biological*
  • Prostheses and Implants*


  • Biocompatible Materials