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. 2017 Feb;19(2):145-151.
doi: 10.1080/10286020.2016.1189906. Epub 2016 Jun 3.

Monoterpenes and sesquiterpenes from the marine sediment-derived fungus Eutypella scoparia FS46

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Monoterpenes and sesquiterpenes from the marine sediment-derived fungus Eutypella scoparia FS46

Hong-Xin Liu et al. J Asian Nat Prod Res. 2017 Feb.

Abstract

Eutypellol A (1), the first norsesquiterpenoid of sequicarene family, as well as eutypellol B (2), a rare 7-methyl oxidized 2-carene derivative, and one new natural product 2-(2-hydroxy-4-methylcyclohex-3-enyl)propanoic acid (3), along with eight known terpenoids, were isolated from the marine sediment-derived fungus Eutypella scoparia FS46 collected from the South China Sea. Their structures were established on the basis of extensive spectroscopic analysis. Compounds 1-3 were evaluated for their antibacterial activities against Staphylococcus aureus and cytotoxic activities against MCF-7, NCI-H460, and SF-268 tumor cell lines.

Keywords: Eutypella scoparia; eutypellol A; eutypellol B.

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