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. 2016 Dec 2;226:7-13.
doi: 10.1016/j.virusres.2016.05.026. Epub 2016 May 31.

Porcine Epidemic Diarrhea in China

Free PMC article

Porcine Epidemic Diarrhea in China

Dang Wang et al. Virus Res. .
Free PMC article


Porcine epidemic diarrhea (PED) is a contagious intestinal disease caused by Porcine epidemic diarrhea virus (PEDV) that characterized by vomiting, diarrhea, and dehydration. PEDV was first identified in the 1980s in China, and since then, it has become one of the most common viral causes of diarrhea. In October 2010, a large-scale outbreak of PED caused by a PEDV variant occurred in China, resulting in tremendous economic losses. This review presents a comprehensive description of PEDV history, prevalence, molecular features, and prevention and control strategies in China.

Keywords: China; Molecular characteristics; Porcine epidemic diarrhea virus; Prevalence; Prevention.


Fig. 1
Fig. 1
Genotyping the PEDV strains in China based on a full-length genomic sequence analysis. Phylogeny-based genotyping of 62 PEDV strains in China for which complete genomic sequences were available. The tree was constructed with the neighbor-joining method, and bootstrap values from 1000 resamplings are shown for each node. The tree is drawn to scale, with branch lengths in the same units as those of the evolutionary distances used to infer the phylogenetic tree. The evolutionary distances were computed using the Maximum Composite Likelihood method and are in the units of the number of base substitutions per site. Evolutionary analyses were conducted in MEGA7. The names of the strains, years and places of isolation, GenBank accession numbers, and genogroups and subgroups proposed in this study are shown.

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