Radiation Effects in the Mediastinum and Surroundings: Imaging Findings and Complications

Semin Ultrasound CT MR. 2016 Jun;37(3):268-80. doi: 10.1053/j.sult.2015.11.002. Epub 2015 Nov 6.


Radiotherapy is one of the cornerstones for treatment of patients with cancer. Although advances in radiotherapy technology have considerably improved radiation delivery, potential adverse effects are still common. Postradiation changes to the mediastinum can include different structures such as the heart, great vessels, and esophagus. The purpose of the article was to illustrate the expected variety of changes to the mediastinum and adjacent lung resulting from external beam radiotherapy and radiotherapy-induced complications to the mediastinum and to discuss different radiotherapy delivery techniques.

Publication types

  • Review

MeSH terms

  • Humans
  • Lung / radiation effects*
  • Mediastinum / radiation effects*
  • Radiation Injuries / etiology*
  • Radiotherapy / adverse effects*
  • Risk Factors