Orbital exenteration at the Mayo Clinic. 1967-1986

Ophthalmology. 1989 Apr;96(4):468-73. doi: 10.1016/s0161-6420(89)32872-7.


Orbital exenteration was performed in 102 patients at the Mayo Clinic during the 20-year period from 1967 through 1986. The surgical procedure was performed for mucormycosis in one patient and for pain and deformity after a severe facial burn in another; in the remaining 100 patients, exenteration was used to treat a neoplastic disorder. Although 19 different neoplasms were encountered, squamous cell carcinoma, basal cell carcinoma, and melanoma constituted 70% of the total. In 82 patients with no known residual tumor or metastases at operation, the 1-year survival rate was 88.6%, the 5-year rate was 56.8%, and the 5-year rate free of recurrence or metastases was 48.3%. In 18 patients with known residual tumor or metastases at exenteration, 55.0% were alive 1 year postoperatively, and the 5-year survival rate was 25.8%. Unusual findings in this series included two patients with metastatic basal cell carcinoma and one patient with a metastatic thyroid Hürthle cell carcinoma.

Publication types

  • Comparative Study
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Eye Enucleation*
  • Eye Injuries / etiology
  • Eye Injuries / surgery
  • Female
  • Hospitals, Proprietary
  • Humans
  • Male
  • Melanoma / diagnosis*
  • Middle Aged
  • Mucormycosis / surgery
  • Orbital Neoplasms / surgery
  • Prognosis
  • Time Factors