We report a case of a 68 year old male who presented with an acute onset of anuric renal failure. Investigations revealed a histologically confirmed “double-positive” anti-GBM disease with initially undetectably high antibody values. An induction therapy with plasma exchange, cyclophosphamide and initially high dose steroids and further maintenance therapy for three months was initiated. The patient remained dialysis-dependent despite partial recovering of renal function. Without pulmonary involvement there were no clues for Goodpasture’s disease. Renal prognosis is unfavourable.
Keywords: Goodpasture-Syndrom; Gooodpasture Syndrome; Plasmapherese; acute renal failure; akutes Nierenversagen; plasmaexchange; rapid-progressive Glomerulonephritis; rapidly progressive glomerulonephritis; «doppelt positive» Anti-GBM- Erkrankung; “double positive” anti GBM disease.