Diverticular Abscess Managed With Long-term Definitive Nonoperative Intent Is Safe

Dis Colon Rectum. 2016 Jul;59(7):648-55. doi: 10.1097/DCR.0000000000000624.

Abstract

Background: Initial nonoperative management of diverticular abscess has become the standard of care; however, the need for elective resection after this index episode is unclear.

Objective: The purpose of this study was to assess the long-term outcomes of expectant management after initial nonoperative treatment of diverticular abscess.

Design: This was a retrospective chart review with prospective telephone follow-up of patients.

Settings: The study was conducted at a large tertiary academic colorectal surgery practice in Canada.

Patients: Adult patients with CT-documented acute sigmoid diverticulitis complicated by abscess managed nonoperatively from 2000 to 2013 were included.

Interventions: Long-term definitive nonoperative management of diverticular abscess.

Main outcome measures: The primary outcome was emergency sigmoidectomy or death from recurrent diverticulitis. Secondary outcomes were recurrent diverticulitis and elective sigmoidectomy for diverticulitis.

Results: Of 135 patients with acute diverticulitis complicated by abscess, a total of 73 patients were managed with nonoperative intent and long-term expectant management. The median follow-up was 62 (Q1 to Q3: 28-98) months. After resolution of the index episode, 22 patients [30.1% (95% CI, 19.6%-40.6%)] experienced a recurrent episode of diverticulitis at a median of 23 (range, 9-40) months. Two patients [2.7% (95% CI, -1.0% to 6.4%)] had a recurrent episode with peritonitis that required sigmoidectomy with stoma at 6 and 64 months. Both patients underwent reversal after 4 and 8 months. Seven [9.6% (95% CI, 2.8%-16.4%)] patients experienced a complicated recurrence and underwent an elective sigmoidectomy [median time to colectomy, 33 (range, 16-56) months]. Thirteen patients [17.8% (95% CI, 9.0%-26.6%)] experienced an uncomplicated recurrence, all of whom were managed with continued nonoperative intent [median follow-up, 81 (range, 34-115) months]. No mortality occurred. On multivariate logistic regression, female gender (p = 0.048) and a previous episode of uncomplicated diverticulitis before the index diverticular abscess (p = 0.020) were associated with a recurrent episode.

Limitations: This study was limited by its retrospective design and modest sample size.

Conclusions: After initial successful nonoperative management of diverticulitis with abscess, expectant management with nonoperative intent is a safe long-term option with low rates of surgery, especially in the emergency setting. See Video, Supplemental Digital Content 1, on the nonoperative management of diverticular abscess at http://links.lww.com/DCR/A234.

Publication types

  • Video-Audio Media

MeSH terms

  • Abdominal Abscess / etiology
  • Abdominal Abscess / therapy*
  • Aftercare / methods*
  • Aged
  • Colectomy
  • Diverticulitis, Colonic / complications*
  • Diverticulitis, Colonic / diagnostic imaging
  • Diverticulitis, Colonic / mortality
  • Diverticulitis, Colonic / therapy
  • Female
  • Follow-Up Studies
  • Humans
  • Logistic Models
  • Male
  • Middle Aged
  • Prospective Studies
  • Recurrence
  • Retrospective Studies
  • Sigmoid Diseases / complications*
  • Sigmoid Diseases / diagnostic imaging
  • Sigmoid Diseases / mortality
  • Sigmoid Diseases / therapy
  • Treatment Outcome
  • Watchful Waiting*