Tracking Protein S-Fatty Acylation with Proteomics

Chembiochem. 2016 Aug 17;17(16):1488-90. doi: 10.1002/cbic.201600314. Epub 2016 Jul 8.


Recently, Hang and co-workers developed "acyl-PEG exchange" (APE), which allows the investigation of protein S-fatty acylation with mass-tag labelling and gel electrophoresis, methods that are accessible to any biochemistry laboratory.

Keywords: cysteine; lipoproteins; palmitoylation; post-translational modification; proteomics.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Acylation
  • Fatty Acids / chemistry
  • Fatty Acids / metabolism*
  • Humans
  • Molecular Structure
  • Protein S / chemistry
  • Protein S / metabolism*
  • Proteomics*


  • Fatty Acids
  • Protein S