Synthetic Biology Provides a Toehold in the Fight against Zika

Cell Host Microbe. 2016 Jun 8;19(6):752-4. doi: 10.1016/j.chom.2016.05.020.


The World Health Organization has identified the development of a rapid point-of-care diagnostic test for Zika virus as a top research priority. In a recent Cell paper, Pardee et al. (2016) have exploited recent advances in synthetic biology and molecular engineering to deliver a sensitive, affordable, and field-ready Zika test.

MeSH terms

  • Female
  • Genetic Engineering
  • Humans
  • Pregnancy
  • Pregnancy Complications, Infectious / diagnosis
  • Pregnancy Complications, Infectious / virology
  • RNA, Viral
  • Sensitivity and Specificity
  • Synthetic Biology / methods*
  • World Health Organization
  • Zika Virus / genetics
  • Zika Virus / isolation & purification*
  • Zika Virus Infection / diagnosis*
  • Zika Virus Infection / virology


  • RNA, Viral