High wholegrain barley β-glucan lowers food intake but does not alter small intestinal macronutrient digestibility in ileorectostomised rats

Int J Food Sci Nutr. 2016 Sep;67(6):678-85. doi: 10.1080/09637486.2016.1194811. Epub 2016 Jun 9.

Abstract

Using barley cultivars differing widely in β-glucan content, we aimed to determine their effects on small intestinal macronutrient digestion in 24 ileorectostomised rats. The rats were fed 1 of 4 experimental diets, each containing a different barley variety, for 11 d. The diets had a content of 0, 2.1, 2.6 and 4.3 g of β-glucan/100 g. Feed intake and faecal excretion of fat, protein, starch, and non-starch polysaccharides were determined in the final 5 d of the study and apparent macronutrient digestibility calculated. Higher dietary levels of β-glucan (2.6% and 4.3%) lowered feed intake (by 15 and 19%, respectively) but final body weight was only lowered by the 4.3% β-glucan diet relative to rats fed the 0% β-glucan diet (all ps < 0.05). Protein, lipid and starch digestibility was unrelated to the dietary β-glucan content. Higher dietary levels of barley β-glucan lower feed intake of ileorectostomised rats, which is independent of intestinal fermentation and unrelated to macronutrient digestibility.

Keywords: Barley; beta-glucan; fat; fibre; ileorectostomy; macronutrient digestibility; protein; rat; satiety; starch; wholegrain.

MeSH terms

  • Animals
  • Diet
  • Dietary Fats / administration & dosage
  • Dietary Fats / analysis
  • Dietary Proteins / administration & dosage
  • Dietary Proteins / analysis
  • Digestion*
  • Feces / chemistry
  • Fermentation
  • Hordeum / chemistry*
  • Ileostomy*
  • Intestine, Small / metabolism*
  • Male
  • Polysaccharides / administration & dosage
  • Polysaccharides / analysis
  • Rats
  • Rats, Sprague-Dawley
  • Starch / administration & dosage
  • Starch / analysis
  • Whole Grains / chemistry*
  • beta-Glucans / administration & dosage
  • beta-Glucans / analysis*

Substances

  • Dietary Fats
  • Dietary Proteins
  • Polysaccharides
  • beta-Glucans
  • Starch