A novel strategy for spectrophotometric simultaneous determination of amitriptyline and nortriptyline based on derivation with a quinonoid compound in serum samples

Spectrochim Acta A Mol Biomol Spectrosc. 2016 Nov 5:168:235-243. doi: 10.1016/j.saa.2016.06.013. Epub 2016 Jun 7.

Authors

Amir Farnoudiyan-Habibi¹, Bakhshali Massoumi², Mehdi Jaymand³

Affiliations

¹ Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, P.O. Box: 51656-65811, Tabriz, Islamic Republic of Iran.
² Department of Chemistry, Payame Noor University, P.O. Box: 19395-3697, Tehran, Islamic Republic of Iran.
³ Research Center for Pharmaceutical Nanotechnology, Tabriz University of Medical Sciences, P.O. Box: 51656-65811, Tabriz, Islamic Republic of Iran. Electronic address: m_jaymand@yahoo.com.

PMID: 27294553
DOI: 10.1016/j.saa.2016.06.013

No abstract available

Keywords: Amitriptyline; Chloranil; Magnetic solid phase extraction; Nortriptyline; Simultaneous determination; Spectrophotometry.

MeSH terms

Acetaldehyde / chemistry
Amitriptyline / blood*
Amitriptyline / chemistry
Benzoquinones / chemistry
Calibration
Chloranil / chemistry
Humans
Hydrogen-Ion Concentration
Ionic Liquids / chemistry
Limit of Detection
Nanoparticles
Nortriptyline / blood*
Nortriptyline / chemistry
Reproducibility of Results
Solid Phase Extraction / methods*
Spectrophotometry, Ultraviolet / methods*
Time Factors

Substances

Benzoquinones
Ionic Liquids
Chloranil
Amitriptyline
quinone
Nortriptyline
Acetaldehyde