Cannabinoid Poisoning by Hemp Seed Oil in a Child

Pediatr Emerg Care. 2017 May;33(5):344-345. doi: 10.1097/PEC.0000000000000780.


We report a case of mild cannabinoid poisoning in a preschool child, after 3-week ingestion of hemp seed oil prescribed by his pediatrician to strengthen his immune system. The patient presented neurological symptoms that disappeared after intravenous hydration. A possible mild withdrawal syndrome was reported after discharge. The main metabolite of Δ-tetrahydrocannabinol was detected in urine, and very low concentration of Δ-tetrahydrocannabinol was detected in the ingested product. This is, as far as we know, the first report of cannabinoid poisoning after medical prescription of hemp seed oil in a preschool child.

Publication types

  • Case Reports

MeSH terms

  • Cannabinoids / poisoning*
  • Cannabis / adverse effects*
  • Child, Preschool
  • Cytochrome P-450 CYP2C9 / metabolism
  • Cytochrome P-450 CYP3A / metabolism
  • Dronabinol / metabolism
  • Dronabinol / urine*
  • Humans
  • Infusions, Intravenous / methods
  • Male
  • Plant Oils / administration & dosage
  • Plant Oils / adverse effects
  • Plant Oils / therapeutic use*
  • Poisoning / diagnosis*
  • Poisoning / etiology
  • Poisoning / therapy
  • Seeds / adverse effects*
  • Substance Withdrawal Syndrome / diagnosis*
  • Substance Withdrawal Syndrome / etiology
  • Treatment Outcome


  • Cannabinoids
  • Plant Oils
  • Dronabinol
  • Cytochrome P-450 CYP2C9
  • Cytochrome P-450 CYP3A