A Six-Stage Workflow for Robust Application of Systems Pharmacology

CPT Pharmacometrics Syst Pharmacol. 2016 May;5(5):235-49. doi: 10.1002/psp4.12071. Epub 2016 Apr 16.


Quantitative and systems pharmacology (QSP) is increasingly being applied in pharmaceutical research and development. One factor critical to the ultimate success of QSP is the establishment of commonly accepted language, technical criteria, and workflows. We propose an integrated workflow that bridges conceptual objectives with underlying technical detail to support the execution, communication, and evaluation of QSP projects.

MeSH terms

  • Computational Biology / methods*
  • Database Management Systems*
  • Humans
  • Pharmacology, Clinical / methods*
  • Systems Biology / methods*
  • Workflow*