A large field of view two-photon mesoscope with subcellular resolution for in vivo imaging

Elife. 2016 Jun 14:5:e14472. doi: 10.7554/eLife.14472.


Imaging is used to map activity across populations of neurons. Microscopes with cellular resolution have small (.

Keywords: 2-photon; barrel cortex; biophysics; calcium; dendritic spines; mouse; neural coding; neuroscience; structural biology; two-photon.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Brain / physiology*
  • Female
  • Intravital Microscopy / methods*
  • Male
  • Mice
  • Neurons / physiology*
  • Optical Imaging / methods*