[Algae-inhibitory Effect and Mechanism of Plant Source N-Caprylic Acid]

Wei Sheng Yan Jiu. 2016 Mar;45(2):189-93, 199.
[Article in Chinese]


Objective: To research the algae-inhibitory effect and mechanism of a plant source n-caprylic acid extracted from coconut oil on M. aeruginosa.

Methods: The M. aeruginosa were treated with 0, 12.5, 25, 50 and 100 μL/L densities of coconut oil n-caprylic acid respectively. And the change of algal density, cell permeability and antioxidant ability were measured.

Results: The greater the concentration of coconut oil n-caprylic acid, the stronger the inhibition on M. aeruginosa. When the concentration was 100 μL/L and processed time was 96 h, the inhibition ratio on M. aeruginosa reached 99%. Compared with the control group, the algal liquid conductivity, nucleic acid content and protein content of experimental groups increased significantly. The SOD activity enhanced with the increasing of coconut oil n-caprylic acid concentration (under 25 μL/L), but when beyond a certain concentration (exceed 25 μL/L), its activity weakened greatly. And the MDA content increased with the increasing of coconut oil n-caprylic acid concentration.

Conclusion: Coconut oil n-caprylic acid has a significant inhibiting effect on M. aeruginosa. Its mechanism may be largely related to cell membrane permeability change and antioxidant capacity reducing.

MeSH terms

  • Antioxidants
  • Caprylates / pharmacology*
  • Coconut Oil
  • Microcystis / drug effects*
  • Plant Oils / chemistry*


  • Antioxidants
  • Caprylates
  • Plant Oils
  • Coconut Oil