What Factors are Important to Patients when Assessing Treatment Response: An International Cross-sectional Survey

Acta Derm Venereol. 2017 Jan 4;97(1):86-90. doi: 10.2340/00015555-2480.


This study investigated the perspective of international patients on individual symptoms of atopic dermatitis (eczema) in determining treatment response. A questionnaire was developed to evaluate the importance of symptoms from the patient's perspective. Patients were asked: "How important are these features in deciding whether or not a treatment is working?", and rated symptoms on a 5-point Likert scale. Patients were approached via Harmonising Outcome Measures for Eczema (HOME) collaborators and self-selected to take part in the on-line survey. Patients from 34 countries (n = 1,111) completed the survey; of these, 423 (38.3%) were parents of children with eczema. Nine items were rated as being "quite important" or "very important" by more than 80% of the respondents: itch, pain/soreness, skin feels hot or inflamed, bleeding, involvement of visible or sensitive body sites, cracks, sleep difficulties, amount of body affected, and weeping/oozing. These results may be of use in determining the face validity of scales from a cross-cultural patients' perspective.

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Child
  • Child, Preschool
  • Cross-Sectional Studies
  • Dermatitis, Atopic / therapy*
  • Female
  • Humans
  • Internationality
  • Male
  • Middle Aged
  • Outcome Assessment, Health Care*
  • Patient Satisfaction
  • Reproducibility of Results
  • Severity of Illness Index
  • Surveys and Questionnaires