Diagnostic accuracy of methicillin-resistant Staphylococcus aureus nasal colonization to predict methicillin-resistant S aureus soft tissue infections

Am J Infect Control. 2016 Oct 1;44(10):1176-1177. doi: 10.1016/j.ajic.2016.03.039. Epub 2016 Jun 13.

Abstract

Nasal methicillin-resistant Staphylococcus aureus (MRSA) testing at admission to the hospital was found to have a positive likelihood ratio of 8.5 and a negative likelihood ratio of 0.41 for predicting MRSA soft tissue infections. The clinical utility of this test depends on the prevalence of MRSA infection. In high prevalence populations, nasal MRSA is useful to rule in MRSA infections. In low prevalence populations it may be useful to rule out infections.

Keywords: Sensitivity and specificity; methicillin-resistant Staphylococcus aureus; nasal cavity/microbiology.

MeSH terms

  • Cohort Studies
  • Connecticut / epidemiology
  • Female
  • Hospitalization
  • Humans
  • Male
  • Methicillin / pharmacology
  • Methicillin Resistance
  • Methicillin-Resistant Staphylococcus aureus / isolation & purification*
  • Middle Aged
  • Nasal Cavity / microbiology
  • Prevalence
  • Sensitivity and Specificity
  • Soft Tissue Infections / epidemiology*
  • Soft Tissue Infections / microbiology
  • Staphylococcal Infections / epidemiology*
  • Staphylococcal Infections / microbiology

Substances

  • Methicillin