Regulatory network of NAC transcription factors in leaf senescence

Curr Opin Plant Biol. 2016 Oct;33:48-56. doi: 10.1016/j.pbi.2016.06.002. Epub 2016 Jun 15.

Abstract

Leaf senescence is finely tuned by many regulatory factors such as NAC (NAM/ATAF/CUC) transcription factors (TFs). NACs comprise one of the largest families of TFs in plants, many of which are differentially regulated during leaf senescence and play a major role in leaf senescence. Recent studies advanced our understanding on the structural and functional features of NAC TFs including target binding specificities of the N-terminal DNA binding domain and dynamic interaction of the C-terminal intrinsically disordered domain with other proteins. NAC TFs control other NACs and also interact with NACs or other TFs to fine-tune the expression of target genes. These studies clearly demonstrated the highly complex characteristics of NAC regulatory networks, which are dynamically regulated temporally and spatially and effectively integrate multiple developmental and environmental signals.

Publication types

  • Review
  • Research Support, Non-U.S. Gov't

MeSH terms

  • Gene Regulatory Networks
  • Plant Development / genetics*
  • Plant Leaves / genetics*
  • Plant Leaves / growth & development
  • Plant Leaves / metabolism
  • Plant Proteins / genetics*
  • Plant Proteins / metabolism
  • Transcription Factors / genetics*
  • Transcription Factors / metabolism

Substances

  • Plant Proteins
  • Transcription Factors