Intensive immunosuppressive therapy for endogenous lipoid pneumonia associated with rheumatoid arthritis

Mod Rheumatol. 2018 Nov;28(6):1044-1048. doi: 10.1080/14397595.2016.1193270. Epub 2016 Jun 20.

Abstract

Endogenous lipoid pneumonia is an uncommon inflammatory pulmonary disease that is caused by lipids from an endogenous source, the treatment for which has not been established. We report the first case of endogenous lipoid pneumonia presenting as lung consolidation and which was associated with rheumatoid arthritis. Treatment was successful with intensive immunosuppressive therapy. When a physician finds lung consolidation in a patient with active rheumatic disease, lipoid pneumonia should be considered.

Keywords: Lipoid pneumonia; Pulmonary involvement; Rheumatoid arthritis.

Publication types

  • Case Reports

MeSH terms

  • Arthritis, Rheumatoid / complications*
  • Bronchoalveolar Lavage / methods
  • Bronchoscopy / methods
  • Cholestasis* / diagnosis
  • Cholestasis* / drug therapy
  • Cholestasis* / etiology
  • Cyclophosphamide / administration & dosage*
  • Dose-Response Relationship, Drug
  • Humans
  • Immunosuppressive Agents / administration & dosage
  • Lung* / diagnostic imaging
  • Lung* / pathology
  • Male
  • Methylprednisolone / administration & dosage*
  • Middle Aged
  • Pneumonia* / diagnosis
  • Pneumonia* / drug therapy
  • Pneumonia* / etiology
  • Tomography, X-Ray Computed
  • Treatment Outcome

Substances

  • Immunosuppressive Agents
  • Cyclophosphamide
  • Methylprednisolone

Supplementary concepts

  • Cholesterol pneumonia