A Case of Urachal Yolk Sac Tumor With Spontaneous Rupture in a Child

J Pediatr Hematol Oncol. 2017 Mar;39(2):e82-e84. doi: 10.1097/MPH.0000000000000615.

Abstract

Tumors arising from urachus in children are exceedingly rare and sporadically reported in literature. Being a midline structure, the urachus may harbor neoplastic germ cell elements and can occasionally present as a case of acute abdomen. A 20-month-old toddler presented with spontaneous rupture of an urachal yolk sac tumor causing hemoperitoneum. He underwent resection, received platinum-based chemotherapy and presently remains well on follow-up. Despite its rarity, urachal germ cell tumors must be considered in a child with acute abdomen and tumor markers must be measured preemptively in such cases.

Publication types

  • Case Reports

MeSH terms

  • Antineoplastic Combined Chemotherapy Protocols / therapeutic use
  • Biomarkers, Tumor / analysis
  • Bleomycin / administration & dosage
  • Carboplatin / administration & dosage
  • Combined Modality Therapy
  • Consanguinity
  • Emergencies
  • Endodermal Sinus Tumor / chemistry
  • Endodermal Sinus Tumor / complications*
  • Endodermal Sinus Tumor / diagnostic imaging
  • Endodermal Sinus Tumor / therapy
  • Etoposide / administration & dosage
  • Hemoperitoneum / etiology*
  • Humans
  • Infant
  • Laparotomy
  • Male
  • Rupture, Spontaneous
  • Tomography, X-Ray Computed
  • Urachus / diagnostic imaging*
  • Urinary Bladder Neoplasms / chemistry
  • Urinary Bladder Neoplasms / complications*
  • Urinary Bladder Neoplasms / diagnostic imaging
  • Urinary Bladder Neoplasms / therapy

Substances

  • Biomarkers, Tumor
  • Bleomycin
  • Etoposide
  • Carboplatin

Supplementary concepts

  • Urachal cancer