Surgical Options for Atypical Facial Pain Syndromes

Neurosurg Clin N Am. 2016 Jul;27(3):365-70. doi: 10.1016/


Atypical neuropathic facial pain is a syndrome of intractable and unremitting facial pain that is secondary to nociceptive signaling in the trigeminal system. These syndromes are often recalcitrant to pharmacotherapy and other common interventions, including microvascular decompression and percutaneous procedures. Herein, the authors present two other viable approaches (nucleus caudalis dorsal root entry zone lesioning and motor cortex stimulation), their indications, and finally a possible treatment algorithm to consider when assessing patients with atypical facial pain.

Keywords: Atypical facial pain; DREZ; Motor cortex stimulation; Nucleus caudalis.

Publication types

  • Review

MeSH terms

  • Facial Pain / surgery*
  • Humans
  • Neurosurgical Procedures / methods*
  • Treatment Outcome