Bone mechanical properties and changes with osteoporosis
- PMID: 27338221
- PMCID: PMC4955555
- DOI: 10.1016/S0020-1383(16)47003-8
Bone mechanical properties and changes with osteoporosis
Abstract
This review will define the role of collagen and within-bone heterogeneity and elaborate the importance of trabecular and cortical architecture with regard to their effect on the mechanical strength of bone. For each of these factors, the changes seen with osteoporosis and ageing will be described and how they can compromise strength and eventually lead to bone fragility.
Keywords: Biomechanics; Bone fragility; Bone loss; Bone resorption; Collagen.
© 2016 Elsevier Ltd. All rights reserved.
Conflict of interest statement
The authors report no conflict of interest related to the content of the manuscript.
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