Opioid Use Disorders

Child Adolesc Psychiatr Clin N Am. 2016 Jul;25(3):473-87. doi: 10.1016/j.chc.2016.03.002. Epub 2016 Apr 9.


Opioid use and addiction in adolescents and young adults is a health problem of epidemic proportions, with devastating consequences for youth and their families. Opioid overdose is a life-threatening emergency that should be treated with naloxone, and respiratory support if necessary. Overdose should always be an opportunity to initiate addiction treatment. Detoxification is often a necessary, but never sufficient, component of treatment for OUDs. Treatment for OUDs is effective but treatment capacity is alarmingly limited and under-developed. Emerging consensus supports the incorporation of relapse prevention medications such as buprenorphine and extended release naltrexone into comprehensive psychosocial treatment including counseling and family involvement.

Keywords: Heroin; Injection; Opioid use disorder; Opioids; Overdose; Prescription opioids; Withdrawal.

Publication types

  • Review

MeSH terms

  • Adolescent
  • Analgesics, Opioid
  • Buprenorphine / therapeutic use
  • Drug Overdose / prevention & control*
  • Humans
  • Naloxone / therapeutic use
  • Naltrexone / therapeutic use
  • Narcotic Antagonists / therapeutic use
  • Opioid-Related Disorders / drug therapy*
  • Opioid-Related Disorders / epidemiology*


  • Analgesics, Opioid
  • Narcotic Antagonists
  • Naloxone
  • Buprenorphine
  • Naltrexone