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. 2016 Oct;22(10):1804-7.
doi: 10.3201/eid2210.152087. Epub 2016 Oct 15.

Chikungunya Virus in Febrile Humans and Aedes Aegypti Mosquitoes, Yucatan, Mexico

Free PMC article

Chikungunya Virus in Febrile Humans and Aedes Aegypti Mosquitoes, Yucatan, Mexico

Nohemi Cigarroa-Toledo et al. Emerg Infect Dis. .
Free PMC article


Chikungunya virus (CHIKV) was isolated from 12 febrile humans in Yucatan, Mexico, in 2015. One patient was co-infected with dengue virus type 1. Two additional CHIKV isolates were obtained from Aedes aegypti mosquitoes collected in the homes of patients. Phylogenetic analysis showed that the CHIKV isolates belong to the Asian lineage.

Keywords: Aedes aegypti; Mexico; Yucatan; alphavirus; chikungunya; chikungunya virus; febrile humans; mosquitoes; vector-borne infections; viruses.


Phylogenetic analysis of chikungunya virus (CHIKV) isolates from Yucatan, Mexico. Analysis was based on a 3,744-nt structural gene region (capsid-E3-E2-6K-E1) of 63 CHIKV isolates, including the 14 isolates from Yucatan. Sequences were aligned by using MUSCLE (11), and the tree was constructed by using the neighbor-joining algorithm as implemented in PHYLIP (12) and using ETE3 (Environment for Tree Exploration 3) (13). Isolates are identified by GenBank accession number, country, and year isolated. CHIKV isolates from the Yucatan are shown in bold. Bootstrap values were generated by using 1,000 repetitions and normalized on a scale of 0–1. Bootstrap values for select branches are shown. 6K, membrane-associated peptide; E, envelope; ECSA, East/Central/South African lineage; IOL, Indian Ocean lineage.

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