Advancements in tetronic acid chemistry. Part 2: Use as a simple precursor to privileged heterocyclic motifs

Moaz M Abdou; Rasha A El-Saeed; Khaled M Elattar; Zeynel Seferoğlu; John Boukouvalas

doi:10.1007/s11030-016-9683-x

Advancements in tetronic acid chemistry. Part 2: Use as a simple precursor to privileged heterocyclic motifs

Mol Divers. 2016 Nov;20(4):989-999. doi: 10.1007/s11030-016-9683-x. Epub 2016 Jun 27.

Authors

Moaz M Abdou¹, Rasha A El-Saeed², Khaled M Elattar², Zeynel Seferoğlu³, John Boukouvalas⁴

Affiliations

¹ Egyptian Petroleum Research Institute, Nasr City, P.O. 11727, Cairo, Egypt. moaz.chem@gmail.com.
² Department of Chemistry, Faculty of Science, Mansoura University, 35516, Mansoura, Egypt.
³ Department of Chemistry, Gazi University, 06500, Ankara, Turkey.
⁴ Département de Chimie, Université Laval, Pavillon Alexandre-Vachon,1045 Avenue de la Médecine, Quebec City, QC, G1V 0A6, Canada.

PMID: 27350109
DOI: 10.1007/s11030-016-9683-x

Abstract

This work highlights the literature of one of the most valuable moieties in the field of organic chemistry. In this review, the chemistry of tetronic acid as a simple precursor to privileged heterocyclic motifs is described. The synthetic procedures of different fused heterocycles incorporating a furan moiety are described. Fused heterocycles are classified as bicyclic, tricyclic, tetracyclic and spiro-fused pyran derivatives.

Keywords: Heterocycles; Multicomponent reactions; Polycyclic systems; Tetronic acid.

Publication types

Review

MeSH terms

Chemistry, Organic*
Furans / chemical synthesis
Furans / chemistry*
Heterocyclic Compounds / chemical synthesis
Heterocyclic Compounds / chemistry*
Structure-Activity Relationship

Substances

Furans
Heterocyclic Compounds
tetronic acid