In women with chronic kidney disease (CKD), pregnancy outcomes have improved over the last 50 years, particularly in the developed world. Maternal mortality is now extremely low, fetal survival has markedly increased (even in women with CKD stages 4-5), and it is now the exception for women with CKD to be advised against embarking on a pregnancy. However, pregnancies are rarely free from complications, and there are unanswered questions about the longer term effects on maternal and infant health. The developments have led to a more optimistic attitude to pregnancy in women with CKD not requiring renal replacement treatment. The remaining problems are described in this World Kidney Forum.
Keywords: CKD; Pregnancy; fetal; infant; kidney disease; maternal; neonatal; outcomes; preeclampsia; renal failure.
Copyright © 2016 National Kidney Foundation, Inc. Published by Elsevier Inc. All rights reserved.