LASIK and surface ablation in patients treated with amiodarone

Arch Soc Esp Oftalmol. 2016 Nov;91(11):520-525. doi: 10.1016/j.oftal.2016.05.005. Epub 2016 Jun 24.
[Article in English, Spanish]


Objective: To determine the anatomical and functional outcomes of corneal refractive surgery in patients on amiodarone, a drug listed as being contraindicated in patients undergoing this procedure.

Material and methods: A retrospective observational study was conducted on all consecutive patients who took amiodarone and who underwent LASIK or surface ablation from January 2003 to December 2014. Functional (visual and refractive) outcomes are described.

Results: A total of 20 patients (33 eyes) were included. No significant intraoperative or postoperative complications were found.

Conclusions: In our experience, LASIK and surface ablation did not produce significant clinical complications in selected patients taking amiodarone. The absolute exclusion of certain systemic medications should be reconsidered.

Keywords: Ablación de superficie; Amiodarona; Amiodarone; Laser Assisted Sub-Epithelial Keratectomy; Laser In Situ Keratomileusis; Photorefractive Keratectomy; Queratectomía Foto-Refractiva; Queratectomía subepitelial asistida por láser; Queratomileusis In Situ Asistida por Láser; Surface ablation.

Publication types

  • Observational Study

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Amiodarone* / adverse effects
  • Anti-Arrhythmia Agents* / adverse effects
  • Contraindications
  • Female
  • Humans
  • Intraoperative Complications / epidemiology
  • Intraoperative Complications / etiology*
  • Keratomileusis, Laser In Situ*
  • Male
  • Middle Aged
  • Postoperative Complications / epidemiology
  • Postoperative Complications / etiology*
  • Retrospective Studies
  • Treatment Outcome


  • Anti-Arrhythmia Agents
  • Amiodarone